The McFall Lab
W E L C O M E !
Our Research
At the McFall lab, we are passionate about conducting groundbreaking research in the cancer field. Our team is dedicated to exploring new mechanisms and data analysis techniques to drive the development of effective cancer treatments. We take pride in our unique approach and are commited to making a difference in the fight against cancer.
Who Are We?
Through the development of isogenic cell line models utilizing CRISPR-Cas9 genome editing, we investigate Ras function in clinically relevant contexts, with particular emphasis on pancreatic ductal adenocarcinoma, non-small cell lung cancer, and colorectal cancer. Our integrated approach combines advanced biochemical and biophysical methodologies to dissect the unique molecular mechanisms underlying individual Ras mutants. This work aims to provide the foundational knowledge necessary for the development of precision oncology strategies, ultimately improving therapeutic outcomes for patients harboring specific Ras alterations.
We would like thank our main sources of funding as we would not be here without them.
